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Category Archives: methods
On “triangulation” in genome scans
Guest contributor K.E. Lotterhos is a marine biologist at Wake Forest University, who studies evolutionary responses to fishing and climate change. You can find her on Twitter under the handle @dr_k_lo. A major goal of evolutionary biology is to understand the genetic … Continue reading
Posted in adaptation, association genetics, genomics, methods, population genetics, quantitative genetics
Tagged evolve-and-resequence, Fst, GEA, GWAS
7 Comments
Why genetic tests are different
In yesterday’s New York Times, Kira Peikoff reported what happened when she took genetic tests for disease risks from three different providers—she got three very different results. 23andMe said my most elevated risks — about double the average — were … Continue reading
Posted in association genetics, medicine, methods
5 Comments
Random drift and phenotypic evolution
This week we have a guest post from Markku Karhunen. Markku’s research at the University of Helsinki included the development and implementation of a number of very interesting and useful population genetics methods. In his guest post Markku discusses these … Continue reading
Posted in adaptation, methods, population genetics, quantitative genetics, R, software, Uncategorized
2 Comments
Getting started with Ultra Conserved Elements
Cross posted on ngcrawford.com If you attended Evolution 2013, you probably heard quite a lot of chatter about ultra conserved elements. Essentially, ultra conserved elements (UCEs) are parts of the genome that are highly conserved between different species. Although UCEs … Continue reading
Posted in genomics, methods, phylogenetics
1 Comment
Scientific computing doesn't have to hurt
Amy Brown handles communication and scheduling for Software Carpentry. The post title alludes to the goals of Software Carpentry, a volunteer organization whose members teach basic software skills to researchers in science, engineering, and medicine. It’s a great organization, and … Continue reading
By popular request …
The original data set of Joshua tree presence locations, which I used as an example in my post about estimating species distribution models in R, is now available for download from Dryad. Thanks to my coauthors for agreeing to share … Continue reading
Posted in data archiving, howto, methods
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Q&A: Julian Catchen helps us dig into STACKS – Part II
As promised, below is part II of our interview with Julian Catchen. These questions focus more on the specifics of using stacks (i.e., user-related questions). Please see the first post if you are interested a general overview. Even more information, … Continue reading
Q&A: Julian Catchen helps us dig into STACKS
Julian Catchen is a post-doctoral researcher at the University of Oregon, where he uses computational solutions to facilitate the analysis of next-generation sequencing data. Prior to obtaining his PhD, Julian worked for both Intel and IBM, experiences that no doubt … Continue reading