Category Archives: genomics

Unbalanced population sampling and STRUCTURE

The utility and intuition offered by the program STRUCTURE, and more generally, the ‘admixture’ model of Pritchard et al. (2000) are unquestioned – with tens of thousands of citations, it retains its lead among the most popular population genetics software. … Continue reading

Posted in bioinformatics, genomics, howto, methods, population genetics, software, STRUCTURE | Tagged , , | 1 Comment

Diving into chilly California waters, understanding genomic differentiation and the role of gene transfer in marine cyanophages

At this point, it’s clear: microbes are everywhere, there are a lot of them, and they are important. In fact, they are more abundant, more diverse and older than any other organism we have on this planet. In particular, cyanobacteria … Continue reading

Posted in Coevolution, evolution, genomics, horizontal gene transfer, microbiology, population genetics | Tagged , , | Leave a comment

The importance of culturing the uncultured, delving into the microbial consortia in the human gut

The molecular side of ecology has grown by leaps and bounds in recent decades. The review we covered not too long ago, did a nice job of summarizing many key aspects highlighting the importance of this relatively new molecular view … Continue reading

Posted in community ecology, genomics, medicine, metagenomics, microbiology | Tagged , , | 2 Comments

Still ruffling feathers after all these years: Darwin's finches and a molecular view of adaptive radiation

One of the many lovely things about molecular ecology is its ability to shine new light on old stories. The well-known case of Darwin’s finches is a classic example of adaptive radiation. These finches demonstrate a clear instance where over time, … Continue reading

Posted in adaptation, association genetics, evolution, genomics, Molecular Ecology, the journal, population genetics, RNAseq, selection, speciation | Tagged , , | 2 Comments

Conifer convergence

Convergent local adaptation is typically studied within a species or between closely related species. In these cases, it is perhaps not unexpected to observe parallel evolution due to common genetic variation, constraints, etc. Convergence between species is somewhat less studied, … Continue reading

Posted in adaptation, association genetics, genomics, plants, selection, Uncategorized | Tagged , , | 1 Comment

The tarsier's nuclear genome comes with a bonus mitochodrial genome

This week Nature Communications published a paper presenting a new genome assembly for Tarsius syrichta, the Phillipine tarsier. Tarsiers are the subject of one of the best of Ze Frank’s “True Facts” videos, and they occupy an interesting place in … Continue reading

Posted in evolution, genomics, natural history | Tagged , , | Leave a comment

The Hidden History of Kiwi Diversification

Of the millions of Earth’s species that likely remain to be described, a majority is thought to be invertebrates, plants, fungi, or microbes. Nevertheless, the pace of species description in some vertebrate groups has not slackened over the past few … Continue reading

Posted in genomics, phylogenetics, phylogeography, species delimitation, Uncategorized | Leave a comment

Divergence and Linked Background Selection

We have widely discussed the reduction in neutral diversity due to demography and linked selection effects (e.g. selective sweeps and hitchhiking, or background selection) in several previous posts (e.g see here, here, and here). However, how linked selection affects neutral divergence … Continue reading

Posted in evolution, genomics, methods, selection, speciation, theory | Tagged , , , , , | 1 Comment

Building bridges across the chaos

In a new review, Eldon and co-authors (in press) attempt to build a bridge across the chaos of genetic patchiness in the sea. They i) describe the patterns characterized as chaotic genetic patchiness, ii) discuss the potential causes of these patterns and … Continue reading

Posted in evolution, genomics, mutation, natural history, next generation sequencing, phylogenetics, phylogeography, population genetics, selection | Tagged , , , | Leave a comment

The almighty CRISPR-Cas9 technology: How does it work?

CRISPR-Cas9 took the whole world of biology by storm. Selected Science’s 2015 Breakthrough of the Year, the CRISPR-Cas9 technology is revolutionizing science. Within five years of the official announcement (Jinek et al. 2012), it became the genome-editing technique of choice. … Continue reading

Posted in evolution, genomics, methods, theory | Tagged , , , | 3 Comments