Author Archives: Noah Snyder-Mackler

How (not) to review papers on inclusive fitness

There are few evolutionary concepts as polarizing as Hamilton’s rule. Some researchers feel that there is no mathematical grounding for it, while others beg to differ. Yet empirical evidence in support of Hamilton’s rule is scarce (but check out this … Continue reading

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Panamanian golden frog skin microbiota predict ability to clear deadly infection

The fungal skin infection, Batrachochytrium dendrobatidis (Bd), has pushed many amphibian species to the brink of extinction. One such species, the Panamanian golden frog, is likely extinct in the wild and has been maintained in captive breeding colonies since 2006. … Continue reading

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Socially structured gut microbiomes in wild baboons

“You can pick your friends and you can pick your nose, but you can’t pick your friend’s nose.” Well, that old adage may still be true, but baboons certainly pick (up) their friends’ gut microbes. A new study by Jenny … Continue reading

Posted in community ecology, genomics, metagenomics, natural history, primates | Tagged , , | 5 Comments

Behavioral individuality reveals genetic control of phenotypic variability

Studies of animal personality (or, “behavioral syndromes”, if you choose your words carefully) are so hot right now. One of the assumptions of such studies is that natural selection has somehow favored this behavioral variability/plasticity (and not just differences in … Continue reading

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This is your brain on Human accelerated regulatory enhancer (HARE5)

Four decades have passed since King and Wilson published their seminal paper “Evolution at Two Levels in Humans and Chimpanzees“. In it, they proposed that the large behavioral and morphological differences between us and our closest relatives, chimpanzees, could not … Continue reading

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THREAT DOWN! Gene flow from polar bears into brown bears

What do you get when you cross a male polar bear with a female brown bear? Trick question: Nothing, because it doesn’t really happen!*

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Life, death, and DNA methylation

You have a molecular clock ticking inside of you and, if you read it properly, it can predict how much longer you will live. Want to know how to read it? Well, grab your DNA methylation profiler of choice, measure … Continue reading

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The microbiome doesn't always explain everything.

Microbiome research is sexy. Just look at the Google Trends graph. Anyone and everyone is studying the gut, nasal, vaginal, skin, oral, aural, any-other-body-part microbiome. This means that a lot of research is getting published saying what constitutes a “healthy” … Continue reading

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New to the genome sequencing $8 menu: Nextera library preps!

Researchers are thrifty. We’re always looking for ways to make our expensive supplies and reagents go the extra mile. This shit has been going on for decades – hell, probably even centuries: I remember when I was a kid and … Continue reading

Posted in genomics, methods, next generation sequencing | Tagged , , , , | 7 Comments

Whip it. Population structure and cross-species transmission of Whipworms

This may be my second worm-related post, but it comes from the PLoS journal that is first in my heart: PLoS Neglected Tropical Diseases. And, as the journal name suggests, it is about a neglected tropical disease: the Whipworm (Trichuris … Continue reading

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