In the journals
Cho YS et al. 2013. The tiger genome and comparative analysis with lion and snow leopard genomes. Nature Communications 4:2433. doi: 10.1038/ncomms3433.
Through comparative genetic analyses of these genomes, we find genetic signatures that may reflect molecular adaptations consistent with the big cats’ hypercarnivorous diet and muscle strength. We report a snow leopard-specific genetic determinant in EGLN1 (Met394Lys39), which is likely to be associated with adaptation to high altitude.
Ferretti L, SE Ramos-Onsins, and M Pérez-Enciso. Population genomics from pool sequencing. Molecular Ecology doi: 10.1111/mec.12522.
Next generation sequencing of pooled samples is an effective approach for studies of variability and differentiation in populations. In this paper we provide a comprehensive set of estimators of the most common statistics in population genetics based on the frequency spectrum, namely the Watterson estimator θW , nucleotide pairwise diversity Π, Tajima’s D, Fu and Li’s D and F , Fay and Wu’s H, McDonald-Kreitman and HKA tests and Fst, corrected for sequencing errors and ascertainment bias.
In the news
Identifying functional variation across the genome using transcriptome sequencing.
Concerning the infamous two-body problem.
An insider account of how faculty hiring committees work.
No, PhDs finding non-academic careers is not a sign that we should make more PhDs.
“She was a professor?” Yeah, but she was an adjunct.
